![]() At the end of 1996 (or was it the beginning of 1997) I started playing with ASReml (programed by Arthur Gilmour mostly based on theoretical work by Robin Thompson and Brian Cullis). ![]() At that time (1995-1996) I moved to DFREML (by Karen Meyer, now replaced by WOMBAT) and AIREML (by Dave Johnson, now defunct-I mean the program), which were designed for the analysis of animal breeding progeny trials, so it was a hassle to deal with experimental design features. A brief history of timeĪt the beginning (1992-1995) I would use SAS (first proc glm, later proc mixed), but things started getting painfully slow and limiting if one wanted to move into animal model BLUP. ![]() The bulk of my use of mixed models relates to the analysis of experiments that have a genetic structure. A substantial part of my job has little to do with statistics nevertheless, a large proportion of the statistical side of things relates to applications of linear mixed models.
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